Drug Development and Innovation Centre
The DDIC aims to bridge the gap between basic sciences and clinical research, working through API with industry and academia to design and create the next generation of therapeutic drug delivery.
With a team of highly specialized researchers and trainees available to assist in the commercialization of modern therapeutic products, the DDIC fosters research and education in pharmaceutical sciences working on translational research and development in the areas of
dr. raimar löbenberg, Founder & Director
Dr. Raimar Löbenberg is an expert in area of pharmaceutics, drug development and delivery. He is a member of the United States Pharmacopoeia (USP) expert committee for Dietary Supplements and Herbal Medicines and chair of the subcommittee for performance testing of dietary supplements, member of the American Association of Pharmaceutical Scientists (AAPS) Steering Committee for Drug Release and Dissolution Testing and vice chair of Speciality Committee for Pharmaceutical Quality of Traditional Medicines of the World Foundation of Traditional Chinese Medicines, and a past president of the Canadian Society for Pharmaceutical Sciences. Contact Dr. Löbenberg.
Dr. Vijay Somayaji, Manager
Dr. Vijay Somayaji has over 30 years of combined academic and biotech industry experience in various areas, including research and development, product development, and quality assurance and quality control. She obtained her Ph.D. in Chemistry from Indian Institute of Science and did her post-doctoral work with Dr. H.C. Brown (Nobel Laureate) at Purdue University (USA). In her various roles, she has managed diverse teams of scientists involved in the characterization of drug substances and drug products, analytical method development (chemical and biochemical), stability testing, clinical sample analyses, and support for regulatory documentation. She has over 50 publications and has been an inventor of two patents. She has also been involved in successful clinical trial applications for more than four drug candidates. Contact Dr. Somayaji.
What we do
The DDIC provides specialized prototypes of novel and conventional dosage forms through testing and production of clinical trial materials in its pharmaceutical test laboratory and Health Canada licensed cleanroom. The Centre’s unique infrastructure allows clinical testing support to take place from study design to finished product with access to a rich and diverse pool of experts.
DDIC offers novel solutions and opportunities in numerous areas for the following groups:
Researchers: Novel delivery systems, Nano Formulations, Design and Proof of Concept Studies
Pharmaceutical Industry: Product Research and Design, Quality Control, Regulatory Affairs, Analytical Testing, Drug Release Testing, Performance Testing, Production (Liquid, Gel, Semi Solid, Solid), Product Life Cycle Management
Clinical Investigators: Joint Clinical Research, Clinical Trial Dosage Forms (Design and Development)
Students and Trainees: Industrial Pharmacy, Regulatory Sciences
Facilities & Equipment
The DDIC’s state-of-the-art equipment is capable of processing small to medium quantities of active pharmaceutical ingredients. It provides researchers with the ability to engage in development and performance analysis of a variety of special and conventional dosage forms ranging from tablets and capsules to microemulsions, ointments, creams and nanoparticles.
The centre adheres to the standards for Good Manufacturing Practices outlined by Health Canada and offers stability testing, according to the protocols of the International Conference on Harmonization (ICH) and received a Health Canada Site License for manufacturing, processing, and packaging in 2009 and has had the license renewed annually.
GMP Compliant Classified Cleanrooms Facility: ISO 6 (Class 1000) and ISO 7 (Class 10,000): for production and packaging, includes a clean room gowning area, clean room formulation facility, clean room filling area
Sterile Products Development Laboratory: for formulation of drug products
GLP Compliant Quality Control Laboratory: for testing of drug products
Prototype Laboratory: for executing project designs
Product Development Equipment
Capsule filling equipment (000, 00, 0, 1)
Double Cone Blender
Fluid Bed Dryer
Fluid Bed Granulator
Grinders for controlled size reduction
Mixers and Blenders
Ointment maker and dispenser
Rotary Tablet Press with instrumentation
Screw Capping Machine
Single Cone Blender
Tablet Counting Machine
Tablet Press and De-Duster
Water Purification System
Quality and Performance Characterization Equipment
Disintegration Testing Apparatus (Top Right)
Dissolution Testing Apparatuses (1, 2) (Top Left)
Flow through Cell (for performance testing of special dosage forms)
Franz Cell (for performance testing of special dosage forms)
HPLC System; HPLC Systems for chemical analysis (Bottom)
Soxhlet Extraction Apparatus
Tablet Hardness Tester
Thermal Activity Monitor
Thermal Conductivity Tester